Boy RN

Topics for Educational Presentations

Peter Bjerkerot, RN, OCN

Cellular: (404) 754-5952

1) Update on Taxane Therapy in Breast Cancer: Nursing Implications and Interventions

OBJECTIVES	CONTENT (Topics)	METHODS
Discuss 3 facts regarding the incidence of Breast Cancer in the USA	• Number of new cases/deaths/survival based on American Cancer Society data • Natural history of Metastatic Breast Cancer (MBC)	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Assess the key challenges associtated with solvents used in the formulation of taxanes	• Clinical trial data from recent studies • Albumin based taxanes vs solvent based taxanes • SAE's associated with solvents used in conventional taxanes	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
List 3 nursing considerations when caring for patients treated with albumin based taxanes and 3 nursing interventions for each.	• Solvent based paclitaxel (Taxol)(SAE and interventions) • Docetaxel (Taxotere)(SAE and interventions) • Albumin based paclitaxel (Abraxane)(SAE and interventions) • Anti-hypersensitivity agents (SAE and interventions)	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.

2) Update on Multiple Targeted Agents in Oncology: Nursing Implications and Interventions

OBJECTIVES	CONTENT (Topics)	METHODS
Discuss the role of signal transduction pathways. Identify 3 abnormal functions that are characteristic of cancer cells.	How ligands bind to and activate receptors. How an activated receptor internalizes the signal and can activate a protien within the cell. How this communication network leads to regualtion of cell division, programmed cell death and expression of certain growth factors. How mutations in cancer cells cause them differ from these normal functions	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Describe 2 goals of multiple targeted agents and their effect on halting cancer cell growth and proliferation	Blocking specific signals in cancer cells and its effects that lead to the arrest of tumor cell proliferation and spare normal cells. When tumors caused by a single mutation are able to again mutate over time, single target agents effectiveness diminishes. Using agents that have target multiple receptors, cancer patients with most cancers may still find benefit	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
List 2 specific cancer types that are being treated with multiple targeted agents and 3 side effects that may be seen in patients undergoing treatment with this type of therapy.	Renal Cell Carcinoma Gastrointestinal Stromal Tumors	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.

3) Update on Endocrine Manipulation in Breast Cancer: Nursing Implications and Interventions

OBJECTIVES	CONTENT (Topics)	METHODS
Discuss 3 facts regarding the history of hormonal manipulation in Breast Cancer.	• Natural history of Breast Cancer • Background of non-chemotherapeutic approaches in the treatment of breast cancer	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Outline 2 treatment options for the patient undergoing endocrine manipulation for Breast Cancer	• Clinical trial data from recent studies • Single agent vs combination • Options for relapsed patients	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Describe 3 hormonal agents used in Brest Cancer and 3 side effects and nursing interventions for each.	• Agonist/antagonist therapies (SAE and interventions) • Pure antagonist therapies (SAE and interventions) • Aromatase inhibitor containing therapies (SAE and interventions)	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.

4) Infusion Reactions in Colorectal Cancer Treatment with Targeted Therapies: Nursing Implications and Interventions

OBJECTIVES	CONTENT (Topics)	METHODS
Describe 2 types of monoclonal antibodies used in the treatment of the Oncology Patient	• Presentation of targeted therapies aimed at cancer cells or their supporting mechanisms • Rules for naming monoclonal antibodies and the impact it has on nursing care	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Outline 3 common types of infusion reactions seen in patients undergoing treatment with monoclonal antibodies.	• Human Antibodies against Mouse Antibodies (HAMA) • Human Antibodies against Chimeric Antibodies (HACA) • Human Antibodies against Humanized Antibodies (HAHA)	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
Describe 3 common side effects associated with Infusion reactions in monoclonal antibodies.	• Acute side effects seen while antibody is being infused • Intermediate side effects shortly after infusion • Long term side effects	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.

5) Update on Renal Cell Cancer: Nursing Implications and Interventions

OBJECTIVES	CONTENT (Topics)	METHODS
1) Discuss 3 facts regarding the incidence of Renal Cell Cancer (RCC) in the USA.	• Epidemiology, natural history, and etiological data regarding RCC in USA	Didactic with time for ongoing Q/A
2) Describe 2 treatment options for RCC patients.	• Multiple Tyrosine Kinase Inhibitor therapy • Cytokine Therapy	Didactic with time for ongoing Q/A
3) Describe 3 Therapeutic Agents used in RCC and 3 side effects and nursing interventions common to each agent.	• • Sunitinib • Sorafinib • Interferon • Temsirolimus	Didactic with time for ongoing Q/A

6) Living with Cancer: Helping the Wounded Healer

OBJECTIVES	CONTENT (Topics)		METHODS
1) Describe 4 common phases used by the patient at time of crisis		• Healthy vs. unhealthy defense mechanisms used by patients	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
2) Examine 2 ways how these phases mirror the grief experience of the family and others left behind		• Healthy vs. unhealthy grief behavior	Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.
3) Detail 3 ways that nurses are perceived by the public vs. the reality of the profession and its impact on nurses who work with patients at end of life.	• Comparison of perceived role of the RN vs. the reality • Multiple loss syndrome and how it leads to burnout. • Ways to utilize behavioral and cognitive models in dealing with multiple loss syndrome		Didactic with handouts and A.V. presentation. Group Q/A PRN throughout presentation.